Due to ethical and practical difficulties, the features of the destructive process are known from a small number of observations, and transcriptomic data are remarkably missing. Here we report whole genome transcript analysis validated by quantitative reverse transcription—polymerase chain reaction qRT—PCR and correlated with immunohistological observations for four T1D pancreases collected 5 days, 9 months, 8 and 10 years after diagnosis and for purified islets from two of them. Collectively, the expression profile of immune response and inflammatory genes confirmed the current views on the immunopathogenesis of diabetes and showed similarities with other autoimmune diseases; for example, an interferon signature was detected. The data also supported the concept that the autoimmune process is maintained and balanced partially by regeneration and regulatory pathway activation, e.
They want to know the How?
This is absolutely necessary in Physical Education since questioning clears doubts and clarifies issues in the minds of individuals. Our body is made for mobility with bones, muscles, tendons, joints and ligaments and knowledge of how and why they function is a necessity.
Therefore it is incumbent for Physical Education be a compulsory subject in our schools.
The body can be compared to a machine and unless it receives gasoline and oil and is properly serviced then its efficiency decreases and it will not function at its optimum, then longevity and a disease-free body will be affected. Instead inactivity and obesity have become serious health concerns.
As physical activity decreases obesity and its attendant illnesses increases.
Students participating in a physical education session as part of the school cirriculum. In a world where heart diseases, sexually transmitted diseases, hypertension and drug abuse are rampant, teaching people to develop healthy lifestyles especially through exercise is invaluable.
Physical education and other subjects There is definitely inter-relatedness between Physical Education and other subjects — Biology, Physics, Maths and Home Economics. This augurs well for Physical Education to be introduced into schools and in streaming, this subject should be included since they will enhance each other.
Many persons spend their money and time in unhealthy life practices and have to go back again spending money and time in correcting this. Job opportunities — career With the increase in Technology and the decrease in working hours, man has a greater amount of leisure time on his hands.
This accounts for a variety of job opportunities and professions where meaningful employment can be gained. Benefits of physical education.EXPORTER OF PAPER.
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PHYSICAL SCIENCES SCHOOL-BASED ASSESSMENT EXEMPLARS – 5 CAPS GRADE 12 TEACHER GUIDE 3. ASSESSMENT TASKS FOR GRADE 12 PRACTICAL WORK The table below lists the prescribed formal assessment activities for practical work and the weighting for the annual SBA.
New curriculum- scheme of work including developing skills, making and applying decisions, developing physical and mental capacity, evaluating and improving and healthy lifestyles.